#
# This is an updated and extended list of non-specific binders. It is based on the original list 
# of non-specific binders at http://www.russelllab.org/wiki/index.php/Non-specific_ligand-protein_binding
#
# Below is the summary of modifications.
#
#
# The following non-specific binders were added:
#
#		DI(HYDROXYETHYL)ETHER;;PEG;
#		BENZAMIDINE;;BEN;
#		NONAETHYLENE GLYCOL;;2PE;
#		HEXAETHYLENE GLYCOL;;P6G
#		PENTAETHYLENE GLYCOL;;1PE;
#		DEUTERATED WATER;;DOD;
#		ACETYL GROUP;;ACE;
#		BENZOIC ACID;;BEZ;
#		BETA-D-XYLOPYRANOSE;;XYP;
#		2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE;;NDG;
#		SELENOMETHIONINE;;MSE;
#		PHOSPHATE ION;;PO4;
#		VANADATE ION;;VO4;
#		4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID;;EPE;
#		2-(N-MORPHOLINO)-ETHANESULFONIC ACID;;MES;
#		2-METHOXYETHANOL;;MXE;
#		XENON;;XE;
#
#
# The following ions were removed from the original list, since they can be specific. 
# A thorougher examination needs to be made in such cases (e.g., determine conservation):
#
#		ZINC ION ON 3-FOLD CRYSTAL AXIS;ZN1;ZN2;
#		ZINC ION ON 3-FOLD CRYSTAL AXIS;ZN1;ZN;
#		ZINC ION;ZN1;ZN;
#		BARIUM ION;BA1;BA;
#		CALCIUM ION;CA1;CA;
#		COBALT (II) ION;CO1;CO;
#		COBALT (III) ION;CO1;3CO;
#		COBALT HEXAMMINE ION;H18 N6 CO1;NCO;
#		COPPER (I) ION;CU1;CU1;
#		COPPER (II) ION;CU1;CU;
#		FE (II) ION;FE1;FE2;
#		FE (III) ION;FE1;FE;
#		MAGNESIUM ION;MG1;MG;
#		MANGANESE (II) ION;MN1;MN;
#		MANGANESE (III) ION;MN1;MN3;
#		NICKEL (II) ION;NI1;NI;
#		NICKEL (III) ION;NI1;3NI;
#
(4-CARBOXYPHENYL)(CHLORO)MERCURY;C7 H5 O2 CL1 HG1;BE7;
(4R)-2-METHYLPENTANE-2,4-DIOL;C6 H14 O2;MRD;
(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID;C6 H10 N2 O5;MHA;
(R,R)-2,3-BUTANEDIOL;C4 H10 O2;BU3;
1,2-ETHANEDIOL;C2 H6 O2;EDO;
1,2-PROPANEDIOL;C3 H8 O2;PGO;
1,3-BUTANEDIOL;C4 H10 O2;BU2;
1,3-PROPANEDIOL;C3 H8 O2;PDO;
1,4-BUTANEDIOL;C4 H10 O2;BU1;
1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE;C12 H26 O6;PG6;
1-BUTANOL;C4 H10 O1;1BO;
1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL;C14 H30 O7 S1;PE7;
1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE;C8 H18 O4;PG5;
10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE;C21 H24 N3 F3 S1;TFP;
2,4-DIHYDROXY-5-OXO-HEXA-2,3-DIENOIC ACID;C5 H4 O6;DHD;
2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL;C55 H112 O28;PEU;
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL;C4 H12 N1 O3;TRS;
2-AMINOETHANESULFONIC ACID;C2 H7 N1 O3 S1;TAU;
2-BUTANOL;C4 H10 O1;SBT;
2-HYDROXYBENZOIC ACID;C7 H6 O3;SAL;
2-METHYL-2,4-PENTANEDIOL;C6 H14 O2;MPD;
2-PROPANOL, ISOPROPANOL;C3 H8 O1;IOH;
2-PROPANOL, ISOPROPANOL;C3 H8 O1;IPA;
2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHANOL;C6 H14 O4;PGE;
2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHANOL;C6 H14 O4;PIG;
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL;C11 H26 N2 O6;B3P;
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL- PROPANE-1,3-DIOL;C8 H19 N1 O5;BTB;
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID;C8 H17 N1 O3 S1;NHE;
2-{2-[2-(2-OCTYLOXYETHOXY)-ETHOXYL]-ETHOXY}ETHANOL;C16 H34 O5;C8E;
2-{2-[2-(2-OCTYLOXYETHOXY)-ETHOXYL]-ETHOXY}ETHANOL;C16 H34 O5;OTE;
2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL;C16 H34 O8;PE4;
3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL;C20 H42 O11;XPE;
3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL;C16 H34 O9;PE8;
3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL;C14 H30 O8;P33;
3,6,9,12,15-PENTAOXATRICOSAN-1-OL;C18 H38 O6;N8E;
3-N-OCTANOYLSUCROSE;C20 H36 O12;2OS;
3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE;C8 H11 N1 O3 S1;1PS;
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE;C32 H58 N2 O7 S1;CPS;
3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE;C12 H19 N1 O3 S1;DMX;
3[N-MORPHOLINE]PROPANE SULFONIC ACID;C7 H15 N1 O4 S1;MPO;
4,5-DEHYDRO-D-GLUCURONIC ACID;C6 H8 O7;GCD;
4,5-DEHYDRO-L-IDURONIC ACID;C6 H8 O7;IDT;
4-DEOXYGLUCARATE;C6 H8 O7;DXG;
5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE;C23 H42 O11;CM5;
6-AMINOHEXANOIC ACID;C6 H13 N1 O2;ACA;
ACETATE ION;C2 H3 O2;ACT;
ACETONE;C3 H6 O1;ACN;
ACETONITRILE;C2 H3 N1;CCN;
ALPHA-D-GLUCOSE;C6 H12 O6;AGC;
ALPHA-D-GLUCOSE;C6 H12 O6;GLC;
ALPHA-D-MANNOSE;C6 H12 O6;MAN;
ALPHA-[4-(1,1,3,3 - TETRAMETHYLBUTYL)PHENYL]- OMEGA-HYDROXY-POLY(OXY-1,2-ETHANEDIYL;C74 H142 O31;DR6;
ALUMINUM ION;AL1;AL;
AMMONIUM ION;H4 N1;NH4;
AZIDE ION;N3;AZI;
B-NONYLGLUCOSIDE;C15H30O6;BNG;
B-OCTYLGLUCOSIDE;C14 H28 O6;BOG;
BETA-D-GALACTOPYRANOSYL-1-6-BETA-D-GLUCOPYRANOSE;C12 H22 O11;LAK;
BETA-D-GLUCOSE;C6 H12 O6;BGC;
BETA-D-MANNOSE;C6 H12 O6;BMA;
BICINE;C6 H13 N1 O4;BCN;
BROMIDE ION;BR1;BR;
BROMO GROUP;BR1;BR;
BROMO GROUP;BR1;BRO;
CACODYLATE ION;C2 H6 O2 AS1 1-;CAC;
CADMIUM ION;CD1;CD;
CARBOXY GROUP;C1 H1 O2;CBX;
CARBOXY GROUP;C1 H1 O2;FMT;
CARBOXYMETHYL GROUP;C2 H3 O2;ACY;
CARBOXYMETHYL GROUP;C2 H3 O2;CBM;
CARBOXYMETHYL GROUP;C2 H3 O2;CM;
CESIUM ION;CS1;CS;
CHLORIDE ION;CL1;CL;
CHLORO GROUP;CL1;CL;
CHLORO GROUP;CL1;CLO;
CITRATE ANION;C6 H5 O7 3-;FCL;
CITRIC ACID;C6 H8 O7;CIT;
CYANIDE GROUP;C1 N1;CN;
CYANIDE GROUP;C1 N1;CYN;
CYANIDE ION;C1 N1;CYN;
CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE;C24 H44 O11;MA4;
CYSTEINE;C3 H7 N1 O2 S1;BTC;
CYSTEINE;C3 H7 N1 O2 S1;CYS;
D(-)-TARTARIC ACID;C4 H6 O6;TAR;
D-GLUCOSE IN LINEAR FORM;C6 H12 O6;GLO;
D-MANNITOL;C6 H14 O6;MTL;
D-PROLINE;C5 H9 N1 O2;DPR;
D-SORBITOL;C6 H14 O6;SOR;
D-XYLITOL;C7 H16 O5;SYL;
DECYL-BETA-D-MALTOPYRANOSIDE;C22 H42 O11;DMU;
DECYLAMINE-N,N-DIMETHYL-N-OXIDE;C12 H27 N1 O1;DDQ;
DIMETHYL SULFOXIDE;C2 H6 O1 S1;DMS;
DIMETHYLFORMAMIDE;C3 H7 N1 O1;DMF;
DIOXANE;C4 H8 O2;DIO;
DIOXANE;C4 H8 O2;DOX;
DODECAETHYLENE GLYCOL;C24 H50 O13;12P;
DODECYL SULFATE;C12 H26 O4 S1;SDS;
DODECYL-BETA-D-MALTOSIDE;C24 H46 O11;LMT;
ETHANOL;C2 H6 O1;EOH;
ETHYL ACETATE;C4 H8 O2;EEE;
ETHYLENE GLYCOL;C2 H6 O2;EDO;
ETHYLENE GLYCOL;C2 H6 O2;EGL;
FLUORIDE ION;F1;F;
FLUORO GROUP;F1;F;
FLUORO GROUP;F1;FLO;
FRAGMENT OF TRITON X-100;C21 H36 O4;TRT;
FREE CYSTEINE;C3 H7 N1 O2 S1;CYS;
FREE CYSTEINE;C3 H7 N1 O2 S1;FCY;
FRUCTOSE; C6 H12 O6;FRU;
GAMMA-BUTYROLACTONE;C4 H6 O2;GBL;
GLUCOSE;C6 H12 O6;GLC;
GLYCEROL;C3 H8 O3;GOL;
GLYCINE;C2 H5 N1 O2;GLY;
GUANOSINE 5'-DIPHOSPHATE 2':3'-CYCLIC MONOPHOSPHATE;C10 H14 N5 O13 P3;GPX;
HEPTANE-1,2,3-TRIOL;C7 H16 O3;HTO;
HEPTYL 1-THIOHEXOPYRANOSIDE;C13 H26 O5 S1;HTG;
HEPTYL-BETA-D-GLUCOPYRANOSIDE;C13 H26 O6;B7G;
HEXAETHYLENE GLYCOL MONODECYL ETHER;C22 H46 O7;C10;
HEXANE-1,6-DIAMINE;C6 H16 N2;16D;
HEXANE-1,6-DIOL;C6 H14 O2;HEZ;
IODIDE ION;I1;IOD;
IODO GROUP;I1;IDO;
IODO GROUP;I1;IOD;
ISOCITRIC ACID;C6 H8 O7;ICI;
ISOCITRIC ACID;C6 H8 O7;ICT;
ISOPROPYL ALCOHOL;C3 H8 01;IPA;
L(+)-TARTARIC ACID;C4 H6 O6;TLA;
LACTOSE;C12 H22 O11;LAT;
LACTOSE;C12 H22 O11;LBT;
LAURYL DIMETHYLAMINE-N-OXIDE;C14 H31 N1 O1;LDA;
LEAD (II) ION;PB1;PB;
LITHIUM ION;LI1;LI;
MERCURY (II) ION;HG1;HG;
MESO-ERYTRHITOL;C4 H10 O4;MRY;
METHANOL;C1 H4 O1;MOH;
N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXODODECYL)AMINO]-1-PROPANAMINIUM INNER SALT;C19 H38 N2 O3;BEQ;
N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE;C17 H38 N1 O3 S1;C15; 
N-OCTANOYL-N-METHYLGLUCAMINE;C15 H31 N1 O6;MG8;
N-PROPANOL;C3 H8 O1;POL;
NITRATE ION;N1 O3;NO3;
O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENEGLYCOL 500);C31 H65 N1 O10;JEF;
O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL;C14 H28 O8;P4C;
O-DODECANYL OCTAETHYLENE GLYCOL;C28 H58 O9;CE1;
OCTANE 1,8-DIAMINE;C8 H20 N2;DIA;
PENTAETHYLENE GLYCOL MONODECYL ETHER;C20 H42 O6;CXE;
PHENOL;C6 H6 O1;IPH;
PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID);C8 H18 N2 O6 S2;PIN;
POLYETHYLENE GLYCOL (N=34);C69 H140 O35;15P;
POTASSIUM ION;K1;K;
PROPANE-1,2,3-TRIOL;C3 H8 O3;CRY;
PROPANE-1,2,3-TRIOL;C3 H8 O3;GOL;
R-1,2-PROPANEDIOL;C3 H8 O2;PGR;
RUBIDIUM ION;RB1;RB;
S-1,2-PROPANEDIOL;C3 H8 O2;PGO;
S-1,2-PROPANEDIOL;C3 H8 O2;PGQ;
SILVER ION;AG1 1+;AG;
SODIUM ION;NA1;NA;
SPERMIDINE;C7 H19 N3;SPD;
SPERMINE (FULLY PROTONATED FORM);C10 H30 N4 4+;SPK;
SPERMINE;C10 H26 N4;SPM;
STRONTIUM ION;SR1;SR;
SUCROSE;C12 H22 O11;SUC;
SULFATE ANION;O4 S1;SO4;
SULFATE ANION;O4 S1;SUL;
SULFATE ION;O4 S1;SO4;
TERTIARY-BUTYL ALCOHOL;C4 H10 O1;TBU;
TETRAMETHYLAMMONIUM ION;C4 H12 N1 1+;TMA;
THEOPHYLLINE;C7 H8 N4 O2;TEP;
THIOCYANATE ION;C1 N1 S1;SCN;
TREHALOSE;C12 H22 O11;TRE;
TRIETHYLENE GLYCOL;C6 H14 O4;PGE;
TRIFLUOROETHANOL;C2 H3 O1 F3;ETF;
TRIS-HYDROXYMETHYL-METHYL-AMMONIUM;C4 H12 N1 O3;144;
UNDECYL-MALTOSIDE;C23 H44 O11;UMQ;
UREA;C1 H4 N2 O1;URE;
YTTRIUM (III) ION;Y1;YT3;
YTTRIUM ION;Y1;Y1;
DI(HYDROXYETHYL)ETHER;;PEG;
BENZAMIDINE;;BEN;
NONAETHYLENE GLYCOL;;2PE;
HEXAETHYLENE GLYCOL;;P6G
PENTAETHYLENE GLYCOL;;1PE;
DEUTERATED WATER;;DOD;
ACETYL GROUP;;ACE;
BENZOIC ACID;;BEZ;
BETA-D-XYLOPYRANOSE;;XYP;
2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE;;NDG;
SELENOMETHIONINE;;MSE;
PHOSPHATE ION;;PO4;
VANADATE ION;;VO4;
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID;;EPE;
2-(N-MORPHOLINO)-ETHANESULFONIC ACID;;MES;
2-METHOXYETHANOL;;MXE;
XENON;;XE;